RNA Details
Disease Name
liver cirrhosis
Tissue
liver
RNA Symbol
CFTR
RNA ID
RNA Type
mRNA
Alteration Pattern
histone deacetylase
Species
homo sapiens
Detection Methods
miRNA microarray chip detection analysis; qmiRNA microarray chip detection; immunoblotting etc.
Target
CFTR
Pathway
WNT SIGNALING PATHWAY
PubMed ID
Title
The epigenetic signature of CFTR expression is co-ordinated via chromatin acetylation through a complex intronic element
Year
2007
Function
Hdac2 may play a pivotal role in hscs activation and liver fibrosis while deregulation of hdacs may serve as a novel mechanism underlying liver fibrosis.